Trachoma Control: The Lancet Features Groundbreaking SAFE Strategy Study, Article  
 
  11 Aug 2006  
 
  The Lancet Features SAFE Article by Carter Center Trachoma Control Director

Carter Center Photo
A Sudanese girl in Eastern Equatoria State takes a dose of banana-flavored azithromycin to protect herself from the bacteria that causes trachoma. Young children carry the highest burden of active trachoma infection and annual mass distribution of antibiotics is recommended for communities where more than 10 percent of young children suffer from the disease. Recent studies have shown that communities in southern Sudan receiving mass antibiotic distribution in conjunction with other interventions in the SAFE strategy have benefited from lower incidences of trachoma and trichiasis.

Learn more about the Carter Center's work in Sudan.
Effect of three years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study



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The Carter Center’s trachoma control efforts continue to transform lives in affected communities. An article published in The Lancet's Aug. 12, 2006, issue indicates that trachoma prevention initiative known as the SAFE strategy (surgery, antibiotics, facial cleanliness, and environmental improvement) applied to targeted communities in southern Sudan reduced prevalence of active trachoma, and unclean faces by up to 92 percent and 87 percent, respectively.

The groundbreaking results of this study provide hope that if the strategy can be implemented successfully in southern Sudan (an area with limited resources, little infrastructure, and difficulties in access and insecurity) the strategy can be implemented effectively in other trachoma-endemic countries. In addition, the study raises opportunity for future research on the collateral health benefits that SAFE strategy can provide toward prevention of other communicable diseases such as diarrhoea, intestinal helminths, pneumonia and malaria.

The article's authors include Carter Center Consultant Dr. Jeremiah Ngondi, and Dr. Paul Emerson, technical director of the Carter Center’s Trachoma Control Program. The University of Cambridge partnered with the Center on this article.

The Carter Center thanks all of its donors and following institutional partners: Conrad N. Hilton Foundation, Lions Clubs International Foundation, and Pfizer Inc.